False-negative hydroxyamphetamine (Paredrine) test in acute Horner's syndrome.

Abstract

PURPOSE:

To describe a false-negative hydroxyamphetamine test.

METHOD:

Two patients with acute unilateral Horner's syndrome whose pupils initially dilated equally to hydroxyamphetamine had pharmacologic localization to the postganglionic nerve in the second week following the onset of symptoms.

RESULTS:

Neuroimaging confirmed the postganglionic location in both cases.

CONCLUSION:

Falsely negative localization with hydroxyamphetamine can occur during the first week after injury, during which time the function of the boutons at the presynaptic terminal is lost.

• Authors: S P Donahue, P J Lavin, K Digre
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 122 Issue 6 Pg. 900-1 (Dec 1996) ISSN: 0002-9394 [Print] United States
• PMID: 8956653 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Mydriatics
• Ophthalmic Solutions
• p-Hydroxyamphetamine

Topics

• Acute Disease
• Adult
• False Negative Reactions
• Horner Syndrome (diagnosis)
• Humans
• Male
• Middle Aged
• Mydriatics
• Ophthalmic Solutions
• Ophthalmology (methods)
• Predictive Value of Tests
• Pupil (drug effects)
• p-Hydroxyamphetamine