Abstract | PURPOSE: METHODS: RESULTS:
HLA-DR4 was statistically related to Vogt-Koyanagi-Harada disease (P = .0063), whereas only a trend toward a significant association between the disease and HLA-B41 was found (P = .06). HLA-DQ1 was detected in a disproportionate number of controls (68.9%) compared with patients (37.5%). CONCLUSIONS:
HLA-DR4 was significantly related to Vogt-Koyanagi-Harada disease in Caucasian European patients, specifically in Italian patients, as it was described in other racial groups. No clear relation was found between the ophthalmologic and systemic manifestations of Vogt-Koyanagi-Harada disease and the presence of HLA specificities.
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Authors | P Pivetti-Pezzi, M Accorinti, R A Colabelli-Gisoldi, M P Pirraglia |
Journal | American journal of ophthalmology
(Am J Ophthalmol)
Vol. 122
Issue 6
Pg. 889-91
(Dec 1996)
ISSN: 0002-9394 [Print] United States |
PMID | 8956647
(Publication Type: Journal Article)
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Chemical References |
- Histocompatibility Antigens Class I
- Histocompatibility Antigens Class II
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Topics |
- Adult
- Female
- Histocompatibility Antigens Class I
(immunology)
- Histocompatibility Antigens Class II
(immunology)
- Histocompatibility Testing
- Humans
- Italy
- Male
- Uveomeningoencephalitic Syndrome
(immunology)
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