36 patients submitted to interventions for thoraco-abdominal surgery has been submitted to antalgic post-operatory
therapy with elastomeric pump at a continuous
intravenous infusion and
patient controlled analgesia (PCA). The patients have been randomized in three groups. The patients of the 1 degree group received 30 minutes before of the end of the surgical intervention 30 mg of
Ketorolac. At the end of the
anesthesia came started an infusion of 150 mg of
Ketorolac (5 vials) in 60 ml of isotonic chlorinated
solution at the rate of 0.5 ml/h. The pump had besides the capability of disperse a maximum of 4 bolus/ h, everyone of 0.5 ml, on demand of the patient. The 2 degrees group received a
solution containing 60 ml of
Morphine in 60 ml of isotonic chlorinated
solution with the same formality of administration. The 3 degrees group (placebo) received 60 ml of isotonic chlorinated
solution in pumps from infusion and
Ketorolac intramuscular on demand. To the times T0 (awakening), T1 (3 h), T2 (6h), T3 (12 h), T4 (24 h), T5 (30 h, was collected algometrical consequences according to VAS (Visual Analogous Scale of Sc modification of the PA increase, FC, FR, SatO2.. The obtained results have highlighted like in the 1 degree group, to the 1 degree algometric consequence (T0), there is a good
sedative effect on the
pain (intensity of the middle low
pain 3.70 +/- 1.64); this antalgic effect has also continued in the other consequences effected in the post-operatory. In the 2 degree group to the awakening (T0), the
pain was middle-tall (5.50 +/- 2.32) and an expressive reduction appeared at the time T2 (3.60 +/- 1.35 P < 0.005). In the 3 degrees group have not recorded a diminution of the
pain if not after 24 hours from the end of the intervention deposit the intramuscular antalgic
therapy. In conclusion, the system infusion + PCA represents an indubitable advantage in comparison with the traditional antalgic
therapy as for concern the entity of the reduction of the
pain as because it permits the use of a smaller quality of drugs.