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Serum alpha 1-antitrypsin concentration in dogs with panniculitis.

AbstractOBJECTIVE:
To measure serum alpha 1-antitrypsin (alpha 1AT) concentration in dogs with histologically confirmed panniculitis to determine whether serum deficiency could cause or exacerbate panniculitis in dogs.
DESIGN:
Cross-sectional, descriptive study.
ANIMALS:
9 dogs (5 with multiple lesions and 4 with solitary lesions).
PROCEDURE:
Serum samples were obtained by means of cephalic or jugular venipuncture and frozen at -20 C until assayed. Serum alpha 1AT concentration was measured by means of radial gel immunodiffusion.
RESULTS:
In all dogs, serum alpha 1AT concentration was within the previously established reference range.
CLINICAL IMPLICATIONS:
In the small number of-dogs studied, panniculitis was not associated with serum alpha 1AT deficiency.
AuthorsD Hughes, M H Goldschmidt, R J Washabau, F Kueppers
JournalJournal of the American Veterinary Medical Association (J Am Vet Med Assoc) Vol. 209 Issue 9 Pg. 1582-4 (Nov 01 1996) ISSN: 0003-1488 [Print] United States
PMID8899021 (Publication Type: Journal Article)
Chemical References
  • alpha 1-Antitrypsin
Topics
  • Adipose Tissue (pathology)
  • Animals
  • Cross-Sectional Studies
  • Dog Diseases (blood, etiology, pathology)
  • Dogs
  • Female
  • Male
  • Panniculitis (blood, etiology, pathology, veterinary)
  • alpha 1-Antitrypsin (analysis)
  • alpha 1-Antitrypsin Deficiency

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