Abstract | OBJECTIVE: PATIENTS: We reviewed the literature and contacted authors who had reported on cerebral Whipple's disease within the last 10 years. Fifteen patients were evaluated, including one patient treated at our hospital and the one presented in this paper. The mean observation period was 41 +/- 37 months (minimum 1 month, maximum 120 months). RESULTS: Four patients had improved and were able to pursue an independent lifestyle, three patients had improved but are still dependent on help with simple activities of daily life, one patient was unchanged, and seven patients had died. Patients with initial penicillin alone had a worse prognosis than patients with initial penicillin plus streptomycin. CONCLUSION:
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Authors | P J Schnider, E C Reisinger, W Gerschlager, C Müller, T Berger, G J Krejs, E Auff |
Journal | European journal of gastroenterology & hepatology
(Eur J Gastroenterol Hepatol)
Vol. 8
Issue 9
Pg. 899-903
(Sep 1996)
ISSN: 0954-691X [Print] England |
PMID | 8889458
(Publication Type: Case Reports, Journal Article, Review)
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Chemical References |
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Topics |
- Anti-Bacterial Agents
- Central Nervous System Diseases
(drug therapy, etiology)
- Drug Therapy, Combination
(therapeutic use)
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Whipple Disease
(complications, drug therapy)
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