Abstract |
Several studies have suggested that the CD4 molecule, in addition to serving as the HIV receptor, may also be involved in postbinding events of HIV infection. The CD4 molecule has been shown to assume an altered conformation on the T-cell surface following HIV binding, which may be involved in these postbinding events.
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Authors | R E Bachelder, N L Letvin |
Journal | Trends in microbiology
(Trends Microbiol)
Vol. 4
Issue 9
Pg. 359-63
(Sep 1996)
ISSN: 0966-842X [Print] England |
PMID | 8885171
(Publication Type: Journal Article, Review)
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Chemical References |
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Topics |
- CD4 Antigens
(chemistry, metabolism)
- HIV
(growth & development)
- HIV Infections
- Humans
- Models, Biological
- Protein Conformation
- Signal Transduction
- T-Lymphocytes
(chemistry, metabolism)
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