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Antibodies against Candida: potential therapeutics?

Abstract
For many years, there has been controversy over the role of antibodies in immunity to Candida, but recently specific antibodies to mannoproteins and hsp90 have been shown to be protective against murine candidiasis. Combined with technical advances in antibody engineering, this raises the possibility of harnessing such antibodies into a new range of therapeutics.
AuthorsR Matthews, J Burnie
JournalTrends in microbiology (Trends Microbiol) Vol. 4 Issue 9 Pg. 354-8 (Sep 1996) ISSN: 0966-842X [Print] England
PMID8885170 (Publication Type: Journal Article, Review)
Chemical References
  • Antibodies, Fungal
  • Antigens, Fungal
  • HSP90 Heat-Shock Proteins
  • Membrane Glycoproteins
  • Receptors, Steroid
  • mannoproteins
Topics
  • Animals
  • Antibodies, Fungal (therapeutic use)
  • Antigens, Fungal (immunology)
  • Candidiasis (prevention & control)
  • Disease Models, Animal
  • HSP90 Heat-Shock Proteins (immunology)
  • Membrane Glycoproteins (immunology)
  • Mice
  • Rats
  • Receptors, Steroid

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