HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Potential dangers from topical preparations containing methyl salicylate.

Abstract
Methyl salicylate (oil of wintergreen) is widely available in many over-the-counter liniments, ointments, lotions or medicated oils for the relief of musculoskeletal aches and pains. Ingestion of methyl salicylate poses the threat of severe, rapid-onset salicylate poisoning because of its liquid, concentrated form and lipid solubility. Excessive usage of these preparations in patients receiving warfarin may result in adverse interactions and bleedings. Methyl salicylate in topical analgesic preparations may cause irritant or allergic contact dermatitis and anaphylactic reactions. Physicians should fully appreciate the potential dangers from topical preparations containing methyl salicylate.
AuthorsT Y Chan
JournalHuman & experimental toxicology (Hum Exp Toxicol) Vol. 15 Issue 9 Pg. 747-50 (Sep 1996) ISSN: 0960-3271 [Print] England
PMID8880210 (Publication Type: Journal Article, Review)
Chemical References
  • Anticoagulants
  • Fixatives
  • Nonprescription Drugs
  • Salicylates
  • Warfarin
  • methyl salicylate
Topics
  • Administration, Oral
  • Administration, Topical
  • Animals
  • Anticoagulants (metabolism, pharmacokinetics)
  • Clinical Trials as Topic
  • Drug Hypersensitivity
  • Drug Interactions
  • Fixatives (adverse effects)
  • Humans
  • Nonprescription Drugs
  • Rats
  • Salicylates (administration & dosage, adverse effects, poisoning)
  • Skin Absorption
  • Warfarin (metabolism, pharmacokinetics)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: