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[Estrogen and progresterone receptors in male breast diseases]

AbstractThe authors study estrogen (RE) and progestogen (RP) receptors by an exchange technique in 8 cases of male breast carcinoma and 7 cases of gynaecomastia. Tumours are considered receptor positive when the binding sites concentration exceeds 100 fmol/g tissue. Using this as a base all the carcinoma are RE+ and 7/8 are RP+. Gynecomastia are always RE- and RP- except for one case which is RP+. RE and RP levels are correlated with the degree of differentiation of the carcinoma, as determined histologically.
AuthorsG Contesso, J C Delarue, F Guerinot, F May-Levin, C Bohuon
JournalLa Nouvelle presse médicale (Nouv Presse Med) Vol. 6 Issue 22 Pg. 1951-3 (May 28 1977) ISSN: 0301-1518 FRANCE
Vernacular TitleRécepteurs aux estrogènes et aux progestogènes en pathologie mammaire chez l'homme.
PMID887385 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Receptors, Estrogen
  • Receptors, Progesterone
Topics
  • Adenocarcinoma (analysis)
  • Adolescent
  • Adult
  • Aged
  • Breast Neoplasms (analysis)
  • Gynecomastia (metabolism)
  • Humans
  • Male
  • Middle Aged
  • Receptors, Estrogen (analysis)
  • Receptors, Progesterone (analysis)