Abstract |
A 17-year-old young man presented with a 2-month sequential visual loss in both eyes. Vision was 20/200 in the right eye and 20/400 in the left eye. Both discs were hyperemic with circumpapillary telangiectasia and nerve fiber swelling. Fluorescein angiography revealed a fuzzy hyperfluorescence due to leakage from dilated capillaries on both discs in the late transit. Molecular mitochondrial DNA study confirmed a homoplasmic 11778 Leber's optic neuropathy.
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Authors | M Y Yen, Y H Wei, J H Liu |
Journal | Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
(J Neuroophthalmol)
Vol. 16
Issue 3
Pg. 178-81
(Sep 1996)
ISSN: 1070-8022 [Print] United States |
PMID | 8865009
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- DNA, Mitochondrial
- Fluoresceins
- Fluorescein
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Topics |
- Adolescent
- Adult
- Capillary Permeability
- DNA, Mitochondrial
(genetics)
- Female
- Fluorescein
- Fluorescein Angiography
- Fluoresceins
(metabolism)
- Fundus Oculi
- Humans
- Male
- Optic Atrophies, Hereditary
(diagnosis, genetics, physiopathology)
- Optic Disk
(blood supply)
- Optic Nerve
(pathology)
- Point Mutation
- Retinal Vessels
(metabolism, pathology)
- Telangiectasis
(pathology)
- Visual Acuity
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