Germinoma arising in the basal ganglia in early stage: CT and MR findings.

Abstract

We report a patient with a germinoma originating in the left basal ganglia. Unenhanced computed tomography (CT) revealed a relatively well-defined high-density lesion, which was slightly enhanced with contrast medium. No tumor stain was noted on angiography. The mass showed hypointensity on T1-weighted magnetic resonance imaging (MRI), and heterogeneous hyperintensity on T2-weighted imaging. The lesion was homogeneously enhanced after the administration of Gd-DTPA. To our knowledge, the MR findings of basal ganglia germinoma have been retrospectively reviewed in just four reported cases, only two of which were examined with Gd-DTPA enhancement. The two cases revealed relatively large masses with cysts and peritumoral edema, and were slightly enhanced after the intravenous injection of Gd-DTPA. Our case was thought to be in the early stage, and its CT and MR findings were slightly different from those of previously reported cases.

• Authors: D Yamana, J Tohyama, T Mike, N Fukaya, M Okano, M Mimura, T Banno, S Ohba
• Journal: Radiation medicine (Radiat Med) 1995 Nov-Dec Vol. 13 Issue 6 Pg. 305-8 ISSN: 0288-2043 [Print] Japan
• PMID: 8850373 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Contrast Media
• Organometallic Compounds
• Pentetic Acid
• Gadolinium
• Gadolinium DTPA

Topics

• Basal Ganglia Diseases (diagnosis, diagnostic imaging)
• Brain Edema (diagnosis)
• Brain Neoplasms (diagnosis, diagnostic imaging)
• Cerebral Angiography
• Child
• Contrast Media
• Cysts (diagnosis)
• Gadolinium
• Gadolinium DTPA
• Germinoma (diagnosis, diagnostic imaging)
• Humans
• Image Enhancement
• Magnetic Resonance Imaging
• Male
• Neoplasm Staging
• Organometallic Compounds
• Pentetic Acid (analogs & derivatives)
• Radiographic Image Enhancement
• Tomography, X-Ray Computed