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[The effect of the alpha-adrenoblocker tropafen on the microcirculation and the hematocrit index in the capillaries of rats with ischemia].

Abstract
The ischemia-induced decrease of the hematocrit index was the greatest in precapillaries and smallest capillaries. Significant oscillations of the index occurred in reperfusion. Tropafen decreased the index. Applied prior to ischemia, tropafen did not affect microcirculation and redistribution of erythrocytes during ischemia and reperfusion.
AuthorsV K Khugaeva, P N Aleksandrov
JournalFiziologicheskii zhurnal imeni I.M. Sechenova (Fiziol Zh Im I M Sechenova) Vol. 81 Issue 6 Pg. 113-21 (Jun 1995) ISSN: 1027-3646 [Print] Russia (Federation)
Vernacular TitleVliianie al'fa-adrenoblokatora tropafena na mikrotsirkuliatsiiu i pokazatel' gematokrita v kapilliarakh krys pri ishemii.
PMID8845869 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Adrenergic alpha-Antagonists
  • Tropanes
  • tropodifene
Topics
  • Adrenergic alpha-Antagonists (pharmacology)
  • Animals
  • Capillaries (drug effects, physiopathology)
  • Dose-Response Relationship, Drug
  • Hematocrit
  • Ischemia (physiopathology)
  • Male
  • Mesentery (blood supply)
  • Microcirculation (drug effects, physiopathology)
  • Rats
  • Time Factors
  • Tropanes (pharmacology)

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