Abstract |
Twenty monoclonal antibodies (MAbs) were produced against the virulent ALD or vaccinal GPE- strains of classical swine fever (CSF) virus. The MAbs were divided into 7 groups on the basis of the difference in the reaction spectrum to various CSF and bovine viral diarrhea-mucosal disease (BVD-MD) viruses. The panel of the MAbs could classify 20 CSF viruses into 6 types, and could discriminate between not only CSF and BVD-MD viruses but also the vaccinal GPE- strain and the field isolates of CSF virus. The results indicated that the MAbs were useful for diagnosis and investigation of CSF viruses.
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Authors | T Nishimori, S Yamada, M Shimizu |
Journal | The Journal of veterinary medical science
(J Vet Med Sci)
Vol. 58
Issue 7
Pg. 707-10
(Jul 1996)
ISSN: 0916-7250 [Print] Japan |
PMID | 8844614
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Animals
- Antibodies, Monoclonal
- Antibody Specificity
- Bovine Virus Diarrhea-Mucosal Disease
(diagnosis)
- Cattle
- Classical Swine Fever
(diagnosis, immunology)
- Classical Swine Fever Virus
(immunology, isolation & purification)
- Diagnosis, Differential
- Diarrhea Viruses, Bovine Viral
(immunology, isolation & purification)
- Japan
- Mice
- Mice, Inbred BALB C
- Swine
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