Correlation between CSWS and aphasia in Landau-Kleffner syndrome: a study of three cases.

We report three typical cases of Landau-Kleffner syndrome with varied courses. The very frequent discharges in sleep EEGs, often showing the patterns of CSWS (continuous spike-waves during slow-wave sleep), either typical (spike-wave complex occupying over 85% of slow-wave sleep duration) or atypical (spike-waves occupying less than 85% of slow-wave sleep), were presented in all our cases. The CSWS seems correlated with aphasia in our cases. Since the disappearance of CSWS might be indicative of a lagged improvement in aphasia, we suggest that sufficiently long-term treatment with anticonvulsants and/or corticosteroids is worthwhile, if the EEG is improved significantly by this treatment.
AuthorsM Li, X Y Hao, J Qing, X R Wu
JournalBrain & development (Brain Dev) 1996 May-Jun Vol. 18 Issue 3 Pg. 197-200 ISSN: 0387-7604 [Print] NETHERLANDS
PMID8836500 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anticonvulsants
  • Anticonvulsants (administration & dosage)
  • Child, Preschool
  • Electroencephalography
  • Humans
  • Landau-Kleffner Syndrome (drug therapy, physiopathology)
  • Male
  • Sleep Stages (physiology)

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