Abstract |
As ovarian Sertoli-Leydig cell tumors are extremely rare, it appears worthwhile to report cases with uncommon clinical and/or laboratory findings. A 37-year-old nulligravida female was referred because of secondary amenorrhea and hirsutism for 11 years. She appeared virilized with a male body habitus. The highest plasma testosterone (T) level was 1,070 ng/dl. A laparotomy with salpingo-oophorectomy was performed and the pathological report confirmed the presence of Sertoli-Leydig cell tumor of intermediate differentiation. Ovarian venous T value was 5,690 ng/dl. The patient was alive and well with improved hirsutism 4 years after the operation. The duration of symptoms and T level in our patient were among the highest values ever recorded in the literature. This supports the slowly progressive nature of the tumor and emphasizes that Sertoli-Leydig cell tumors should be included in the differential diagnosis of patients with elevated T level regardless of the duration of clinical symptoms.
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Authors | C C Tsai, S H Collins, S J Swanger |
Journal | Changgeng yi xue za zhi
(Changgeng Yi Xue Za Zhi)
Vol. 19
Issue 2
Pg. 191-5
(Jun 1996)
China (Republic : 1949- ) |
PMID | 8828265
(Publication Type: Case Reports, Journal Article)
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Topics |
- Adult
- Amenorrhea
(complications)
- Female
- Hirsutism
(complications)
- Humans
- Ovarian Neoplasms
(diagnosis)
- Sertoli-Leydig Cell Tumor
(diagnosis)
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