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Intrathecal baclofen for severe torsion dystonia in a child.

Abstract
The successful use of intrathecal baclofen, a structural analogue of gamma-aminobutyric acid, is described in the treatment of a 9-year-old boy with intractable torsion dystonia, not responding to conservative treatment. To our knowledge, this is the first reported case of continuous intrathecal baclofen for hereditary torsion dystonia. This case suggests that a continuous intrathecal infusion of baclofen may facilitate remission of intractable torsion dystonia, and provides a basis for further investigation of the treatment of intractable childhood dystonia.
AuthorsG Paret, R Tirosh, B Ben Zeev, A Vardi, N Brandt, Z Barzilay
JournalActa paediatrica (Oslo, Norway : 1992) (Acta Paediatr) Vol. 85 Issue 5 Pg. 635-7 (May 1996) ISSN: 0803-5253 [Print] Norway
PMID8827116 (Publication Type: Case Reports, Journal Article)
Chemical References
  • GABA Agonists
  • Baclofen
Topics
  • Baclofen (administration & dosage, therapeutic use)
  • Child
  • Dystonia Musculorum Deformans (drug therapy)
  • GABA Agonists (administration & dosage, therapeutic use)
  • Humans
  • Injections, Spinal
  • Male

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