Abstract |
Lymphoid involvement in acute myeloid leukemia (AML) was studied using the morphology-antibody-chromosome ( MAC) combination technique in one patient. The chromosomal aberration, trisomy 8, was demonstrated in AML blasts, glycophorin A-positive erythroblasts, and CD3- and CD20/22-positive small lymphocytes. This suggests that in this patient even lymphocytes belonged to the leukemic clone.
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Authors | W El-Rifai, M L Larramendy, T Ruutu, S Knuutila |
Journal | Genes, chromosomes & cancer
(Genes Chromosomes Cancer)
Vol. 15
Issue 1
Pg. 34-7
(Jan 1996)
ISSN: 1045-2257 [Print] United States |
PMID | 8824723
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Acute Disease
- Aged
- Cell Differentiation
- Chromosomes, Human, Pair 8
- Female
- Genotype
- Humans
- Immunophenotyping
- Leukemia, Myeloid
(genetics, immunology, pathology)
- Phenotype
- Trisomy
- Tumor Cells, Cultured
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