HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Primary Sjögren's syndrome, ulcerative colitis and selective IgA deficiency.

Abstract
A 24-year-old man with primary Sjögren's syndrome presented with xerophthalmia, xerostomia, and marked parotid swelling. He had a previous history of selective IgA deficiency and ulcerative colitis treated with sulphasalazine. Immunosuppression and withdrawal of sulphasalazine resulted in rapid resolution of the parotitis and disappearance of autoantibodies. A possible role for sulphasalazine in the induction of autoimmunity in this case is discussed.
AuthorsA Steuer, D J McCrea, C B Colaco
JournalPostgraduate medical journal (Postgrad Med J) Vol. 72 Issue 850 Pg. 499-500 (Aug 1996) ISSN: 0032-5473 [Print] England
PMID8796220 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Gastrointestinal Agents
  • Immunosuppressive Agents
  • Sulfasalazine
  • Prednisolone
  • Azathioprine
Topics
  • Adolescent
  • Azathioprine (therapeutic use)
  • Colitis, Ulcerative (complications, drug therapy)
  • Gastrointestinal Agents (adverse effects)
  • Humans
  • IgA Deficiency (chemically induced, complications)
  • Immunosuppressive Agents (therapeutic use)
  • Male
  • Prednisolone (therapeutic use)
  • Sjogren's Syndrome (complications)
  • Sulfasalazine (adverse effects)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: