Immunology of papillomavirus infection.

Abstract

Studies of the immunology of papillomavirus infection have come of age. Synthetic virus-like particles have been validated as vaccines for several animal papillomaviruses, and have been used to map the sero-epidemiology of human papillomavirus infection and to define papillomavirus neutralizing antibodies. Induction of cell-mediated immunity to papillomavirus early proteins is poised to become a therapeutic approach to papillomavirus infection. Studies on the immune response to papillomavirus proteins in keratinocytes are shedding light on the immunological consequences of antigen presentation by epithelial cells.

• Authors: I H Frazer
• Journal: Current opinion in immunology (Curr Opin Immunol) Vol. 8 Issue 4 Pg. 484-91 (Aug 1996) ISSN: 0952-7915 [Print] England
• PMID: 8794007 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., Review)

Topics

• Animals
• Humans
• Papillomaviridae (immunology)
• Papillomavirus Infections (immunology)
• Tumor Virus Infections (immunology)