Toxicological profile of aureofungin: a potent plant antifungal antibiotic.

Abstract	Aureofungin is a heptaene type of antifungal antibiotic used for controlling plant fungal infections and diseases, during pre and post harvesting period of various crops. Acute and subacute oral toxicity of aureofungin in rats was studied along with haematological, urine analysis and other biochemical parameters related to liver and kidney organ functions. The results of these studies indicate mild toxic symptoms at higher doses which were reversible following its withdrawal.
Authors	J N Dhuley, V Shanbhag, P H Raman, A M Mujumdar, S R Naik
Journal	Indian journal of experimental biology (Indian J Exp Biol) Vol. 33 Issue 11 Pg. 857-60 (Nov 1995) ISSN: 0019-5189 [Print] India
PMID	8786162 (Publication Type: Journal Article)
Chemical References	Antifungal Agents Polyenes aureofungin
Topics	Animals Antifungal Agents (administration & dosage, toxicity) Behavior, Animal (drug effects) Kidney (drug effects, physiopathology) Liver (drug effects, physiopathology) Polyenes (administration & dosage, toxicity) Rats Safety

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