Abstract |
It is often difficult to estimate slight alterations in the severity of ataxia by bed-side neurological examinations. We analyzed the heel-knee tapping test, which has often been used as a standard bed-side examination to check incoordination in lower limbs, using a new motion measurement system "video/computer motion measurement system". We studied 9 normal controls and 21 patients with spinocerebellar degenerations (SCD). In patients with SCD, the up-and-down motion range of the heel was variable and the heel moved in the anterior-and-posterior direction, because of knee sways during the test. Following oral administration of TRH analogue, TA-0910, above-mentioned findings were clearly improved. Analysis of spatial and time elements of the knee joint demonstrated quantitative improvement. Therefore, an effect of TA-0910 on incoordination of the lower limbs could be proved objectively by a computer motion measurement system.
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Authors | N Ando, Y Fujimoto, T Takayanagi, M Ando, Y Mano |
Journal | Rinsho shinkeigaku = Clinical neurology
(Rinsho Shinkeigaku)
Vol. 35
Issue 7
Pg. 733-7
(Jul 1995)
ISSN: 0009-918X [Print] Japan |
PMID | 8777795
(Publication Type: English Abstract, Journal Article)
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Topics |
- Adult
- Aged
- Computers
- Heel
(physiopathology)
- Humans
- Knee
(physiopathology)
- Middle Aged
- Spinocerebellar Degenerations
(physiopathology)
- Video Recording
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