Abstract |
Adult female mice, male rats, female hamsters and male guinea pigs received various doses of styrene (150-1000 mg/kg of body weight) and acrylonitrile (20-80 mg/kg of body weight) intraperitoneally. Both styrene and acrylonitrile caused a depression of the hepatic nonprotein sulfhydryl content. Mouse was the most vulnerable and rat the most resistant species to the effect of both of these two important plastic monomers.
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Authors | H Vainio, A Mäkinen |
Journal | Research communications in chemical pathology and pharmacology
(Res Commun Chem Pathol Pharmacol)
Vol. 17
Issue 1
Pg. 115-24
(May 1977)
ISSN: 0034-5164 [Print] United States |
PMID | 877398
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Nitriles
- Styrenes
- Sulfhydryl Compounds
- Acrylonitrile
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Topics |
- Acrylonitrile
(pharmacology)
- Animals
- Cricetinae
- Depression, Chemical
- Female
- Guinea Pigs
- Liver
(drug effects, metabolism)
- Male
- Mesocricetus
- Mice
- Nitriles
(pharmacology)
- Rats
- Species Specificity
- Styrenes
(pharmacology)
- Sulfhydryl Compounds
(metabolism)
- Time Factors
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