Phenytoin-induced toxic epidermal necrolysis: a case report.

Abstract

We present a case of phenytoin-induced toxic epidermal necrolysis resulting in 60-70% skin involvement. Systemic corticosteroids and prophylactic antibiotics used initially were discontinued, and subsequent management concentrated on intensive supportive treatment. The patient survived, but is left with disabling ocular complications.

• Authors: J D Creamer, S J Whittaker, M Kerr-Muir, N P Smith
• Journal: Clinical and experimental dermatology (Clin Exp Dermatol) Vol. 21 Issue 2 Pg. 116-20 (Mar 1996) ISSN: 0307-6938 [Print] England
• PMID: 8759197 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anticonvulsants
• Phenytoin

Topics

• Adult
• Anticonvulsants (adverse effects)
• Eye Diseases (chemically induced, therapy)
• Humans
• Male
• Phenytoin (adverse effects)
• Stevens-Johnson Syndrome (etiology, pathology, therapy)