Aspergillus fumigatus scleritis.

Abstract

We report a case of scleritis caused by Aspergillus fumigatus. The infection was successfully treated with antifungal drugs, cryotherapy and dura mater grafting. A 67-year-old man developed a scleral ulcer 2 months after suffering a trauma in his right eye caused by the branch of a tree. Diagnosis was made after biopsy of a scleral nodule. Scrapings showed hyphal fragments and cultures were positive for Aspergillus fumigatus. Although therapy with oral fluconazol and topical amphotericin B was begun, the scleritis continued to worsen, so cryotherapy and dura mater grafting were performed. The patient showed no signs of infection for 8 months after discontinuation of antifungal drugs.

• Authors: M T Rodriguez-Ares, M V De Rojas Silva, M Pereiro, B Fente Sampayo, G Gallegos Chamas, M S-Salorio
• Journal: Acta ophthalmologica Scandinavica (Acta Ophthalmol Scand) Vol. 73 Issue 5 Pg. 467-9 (Oct 1995) ISSN: 1395-3907 [Print] Denmark
• PMID: 8751132 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antifungal Agents
• Amphotericin B
• Fluconazole

Topics

• Aged
• Amphotericin B (therapeutic use)
• Antifungal Agents (therapeutic use)
• Aspergillosis (etiology, pathology, therapy)
• Aspergillus fumigatus (isolation & purification)
• Cryotherapy
• Dura Mater (transplantation)
• Eye Infections, Fungal (etiology, pathology, therapy)
• Eye Injuries (microbiology, therapy)
• Fluconazole (therapeutic use)
• Humans
• Male
• Scleritis (microbiology, pathology, therapy)