Abstract | OBJECTIVE: To identify different types of low grade B-cell non-Hodgkin's lymphoma (NHL) classified according to the Revised European American Lymphoma and Kiel classification systems by means of digital image processing. STUDY DESIGN: Seventy-four touch imprints were scanned and analyzed. To compare common but intricate DNA stain with a routinely used panoptical dye, all lymphoma specimens had been stained by the Romanowsky-Giemsa method and 48 touch imprints redyed with Feulgen- Azure A. In both cases 30 features derived from size, and chromatin texture of each nucleus were evaluated. RESULTS: CONCLUSION: The application of texture analysis is feasible in the classification of NHL.
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Authors | S Kneitz, G Ott, Albert, T Schindewolf, H K Müller-Hermelink, H Harms |
Journal | Analytical and quantitative cytology and histology
(Anal Quant Cytol Histol)
Vol. 18
Issue 2
Pg. 121-8
(Apr 1996)
United States |
PMID | 8744501
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Azure Stains
- Coloring Agents
- Feulgen stain
- Romanowsky-Giemsa stain
- Rosaniline Dyes
- Eosine Yellowish-(YS)
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Topics |
- Azure Stains
- Coloring Agents
- Eosine Yellowish-(YS)
- Humans
- Lymphoma, Non-Hodgkin
(classification, pathology)
- Reproducibility of Results
- Rosaniline Dyes
- Signal Processing, Computer-Assisted
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