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[Joint and systemic manifestations related to type 2 anti-mitochondrial antibodies]

AbstractThe aim of the study was to assess the significance of type 2 anti-mitochondrial antibodies in patients with systemic and inflammatory rheumatic disease. Articular and systemic manifestations of 8 patients associated with type 2 anti-mitochondrial antibodies are described. All the patients had hepatic abnormalities, and 5 of them disclosed a primary biliary cirrhosis. Articular and systemic manifestations were similar to those observed in primary biliary cirrhosis. Therefore, the finding of anti-mitochondrial antibodies in patients with systemic or inflammatory rheumatic disease implies research for other systemic manifestations such as primary biliary cirrhosis.
AuthorsR Dhôte, B Christoforov, B Weill, C J Menkes (Affiliation: Service de Médecine Interne, Hôpital Cochin, Paris.)
JournalAnnales de médecine interne (Ann Med Interne (Paris)) Vol. 146 Issue 8 Pg. 536-40 ( 1995) ISSN: 0003-410X FRANCE
Vernacular TitleManifestations articulaires et systémiques associées aux anticorps anti-mitochondries de type 2.
PMID8734077 (Publication Type: Case Reports, English Abstract, Journal Article, Review)
Chemical References
  • Antibodies
Topics
  • Aged
  • Aged, 80 and over
  • Antibodies (analysis, physiology)
  • Arthritis (immunology)
  • Arthritis, Rheumatoid (immunology)
  • Female
  • Humans
  • Joint Diseases (immunology)
  • Liver Cirrhosis, Biliary (immunology)
  • Middle Aged
  • Mitochondria (immunology, ultrastructure)
  • Retrospective Studies