Histoplasmosis in the Muñiz Hospital of Buenos Aires.

Abstract

Some epidemiological and immunological characteristics and the methodology of diagnosis of 44 cases of histoplasmosis (HP); 36 (27 males and 9 women) associated with AIDS (HP+AIDS) and 8 (7 males and 1 female) with other predisposing factors (HP+non AIDS), diagnosed in the Muñiz Hospital (MH) during 1994, were retrospectively studied. The median age (MA) of HP+AIDS patients was 28 years; 25.5 (22-40) in the women and 28.5 (20-42) in the men and 50 (22-58) years in the HP+non AIDS patients. The more frequent risk factors for HIV infection were intravenous drug addiction (55%) and homo/bisexuality (19%). The MA of these groups were 28 (20-39) and 41 (26-42) years, respectively. Tobaccoism was a predisposing factor in 83% of HP+non AIDS patients. The muco-cutaneous lesions scraping and blood-cultures established the initial diagnosis in 53% and 36% of HP+AIDS patients, respectively and the muco-cutaneous lesions biopsies in 75% of HP+non AIDS cases. At time of diagnosis, all HP+AIDS patients had < 200 while HP+non AIDS patients had > 200 CD4 + lymphocytes/microliters. Seventy two per cent of HP+AIDS patients were born in Buenos Aires (Bs As) city and 62% of HP+non AIDS patients were born in provinces of Argentina other than Bs As. At moment of diagnosis, 87.5% of HP+AIDS and 62.5% of HP+non AIDS patients lived in Bs As city and Bs As outskirts.

• Authors: A J Bava
• Journal: Revista do Instituto de Medicina Tropical de Sao Paulo (Rev Inst Med Trop Sao Paulo) 1995 Nov-Dec Vol. 37 Issue 6 Pg. 531-5 ISSN: 0036-4665 [Print] Brazil
• PMID: 8731267 (Publication Type: Journal Article)

Topics

• AIDS Serodiagnosis (methods)
• Acquired Immunodeficiency Syndrome (complications)
• Adult
• Argentina (epidemiology)
• Blotting, Western
• CD4-CD8 Ratio
• Chronic Disease
• Female
• Histoplasmosis (complications, diagnosis, epidemiology, immunology)
• Humans
• Male
• Middle Aged