[Effect of prepuberal gonadectomy in partial androgen resistance syndrome].

Abstract

The androgen resistance syndrome, is a dominant and recessive linked to X disorder, with clinically heterogenous manifestations. Reported case. A 17-years patient with primary amenorrhoea and genital ambiguity. Bilateral inguinal herniplastia and probable gonadectomy were performed at 14-months-old. His cariotipe was male 46,XY and the hormonal determinations showed the presence of hypergonadotropic hypogonadismo. The congenital adrenal hyperplasia (deficiency of 21-hidroxilase) was discarded. In the partial androgen resistance syndrome, the prepuberal gonadectomy avoid a progresive virilization of the external genitals. However, the estrogenic hormonal replacement is mandatory.

• Authors: M A Garcia Morales, J Barron Vallejo, L Limon Luque
• Journal: Ginecologia y obstetricia de Mexico (Ginecol Obstet Mex) Vol. 64 Pg. 120-1 (Mar 1996) ISSN: 0300-9041 [Print] Mexico
• Vernacular Title: Efecto de la gonadectomía prepuberal en el Síndrome de Resistencia Parcial a los Andrógenos.
• PMID: 8729188 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Receptors, Androgen

Topics

• Adolescent
• Age Factors
• Disorders of Sex Development (metabolism, physiopathology)
• Estrogen Replacement Therapy
• Female
• Gonads (surgery)
• Humans
• Hypogonadism (etiology)
• Infant
• Karyotyping
• Male
• Receptors, Androgen
• Syndrome
• X Chromosome
• Y Chromosome