Abstract |
The case of an 11 year old girl with three line type of polycythaemia vera, with 4 cm splenomegaly and a plethoric complexion is presented. Peripheral blood values were as follows: RBC: 7.75 x 10(12)/l, Hb: 18.8 g/l, WBC: 15.2 x 10(9)/l, platelets: 920 x 10(9)/l. Serum erythropoietin level: < 1 mU/ml. In vitro, erythroid colonies developed from the bone marrow in the absence of added erythropoetin. For three years the haematocrit value has been controlled by regular venesections. Since extreme thrombocytosis developed, the treatment was continued with interferon alpha. Different treatment protocols are discussed.
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Authors | K Nagy, K Hunyadi, I Fehér, J Tamáska, J Zsíros, R Simkó, I Vámosi |
Journal | Orvosi hetilap
(Orv Hetil)
Vol. 137
Issue 1
Pg. 27-30
(Jan 07 1996)
ISSN: 0030-6002 [Print] Hungary |
Vernacular Title | Valódi polycythaemia 11 éves leányban. |
PMID | 8721860
(Publication Type: Case Reports, English Abstract, Journal Article)
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Chemical References |
- Interferon-alpha
- Erythropoietin
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Topics |
- Age Factors
- Child
- Erythropoietin
(analysis)
- Female
- Hematocrit
- Humans
- Interferon-alpha
(therapeutic use)
- Phlebotomy
- Polycythemia Vera
(complications, drug therapy)
- Splenomegaly
(complications)
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