[Botulinum A toxins in the treatment of spasticity in cerebral palsy during childhood].

Abstract

We evaluated the safety and efficacy of Botulinum- A toxin (BTX) in patients with equinus deformity associated with cerebral palsy (CP). We prescribed BTX to six patients (all of whom had previously participated in a multicenter, randomized, double blind study of the same drug); treatment continued for at least 15 months. Four children showed striking improvement, being converted from toe-toe to consistent or occasional heel-toe gait. No side effects were observed. BTX appears to be safe and effective in patients with CP.

• Authors: P J García Ruiz, V Sánchez Bernardos, V Urcelay, V San Martín, F Castillo, A Ferrer, J Campos, J García de Yébeñes
• Journal: Neurologia (Barcelona, Spain) (Neurologia) Vol. 11 Issue 1 Pg. 34-6 (Jan 1996) ISSN: 0213-4853 [Print] Spain
• Vernacular Title: Tratamiento de la espasticidad asociada a parálisis infantil con toxina botulínica.
• PMID: 8714175 (Publication Type: English Abstract, Journal Article)

Chemical References

• Cholinergic Agents
• Botulinum Toxins

Topics

• Adolescent
• Botulinum Toxins (therapeutic use)
• Cerebral Palsy (complications)
• Child
• Child, Preschool
• Cholinergic Agents (therapeutic use)
• Equinus Deformity (drug therapy, etiology)
• Female
• Humans
• Male
• Treatment Outcome