HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Role of a "bystander" concealed accessory pathway in the response to verapamil and flecainide treatment in a patient with nodal reentry tachycardia].

Abstract
The possibility of multiple accessory atrioventricular pathways as that of multiple atrioventricular "nodal" pathways represents a relatively usual finding in patients suffering from supraventricular reciprocating tachycardias; the occurrence of both double atrioventricular nodal and concealed accessory pathways in the same patient, on the contrary, is far less common, and is usually an unsuspected condition prior to an electrophysiologic endocavitary study. The authors describe a patient suffering from paroxysmal tachycardias of both types, which have been clearly demonstrated by a transesophageal electrophysiological study. The report shows the different effects of two drugs, verapamil and flecainide, on these reciprocating circuits. Flecainide showed an immediate effectiveness in this condition, while verapamil, although very effective for the "nodal" reciprocating tachycardia, might worsen the accessory reentrant one, and cause a "jump" from the first to the second form.
AuthorsC Matteucci, G Busi
JournalGiornale italiano di cardiologia (G Ital Cardiol) Vol. 26 Issue 4 Pg. 419-25 (Apr 1996) ISSN: 0046-5968 [Print] Italy
Vernacular TitleRuolo di una via accessoria occulta "bystander" nella risposta al trattamento farmacologico con verapamil e con flecainide in un paziente affetto da tachicardia da rientro nodale.
PMID8707026 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Anti-Arrhythmia Agents
  • Verapamil
  • Flecainide
Topics
  • Anti-Arrhythmia Agents (therapeutic use)
  • Child
  • Echocardiography
  • Electrocardiography, Ambulatory
  • Flecainide (therapeutic use)
  • Heart Conduction System (physiopathology)
  • Humans
  • Male
  • Tachycardia, Paroxysmal (drug therapy, physiopathology)
  • Tachycardia, Sinoatrial Nodal Reentry (physiopathology)
  • Tachycardia, Supraventricular (drug therapy, physiopathology)
  • Verapamil (therapeutic use)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: