Reproductive function in stallions treated with cambendazole.

Abstract

Twenty stallions were used to determine if the anthelmintic cambendazole affected seminal characteristics, spermatogenesis, concentration of testosterone in blood serum, or weights of the reproductive orgrans. With minor exceptions, significant differences were not found between values for 10 control and 10 stallions treated with a single oral dose (40 mg/kg body weight) of cambendazole. The treatment did not affect reproductive function and it was concluded that the drug should have no effect on the fertility of stallions.

• Authors: R P Amann, J M Bowen, B W Pickett, W E Berndtson, R S Stashak, J L Voss
• Journal: Journal of the American Veterinary Medical Association (J Am Vet Med Assoc) Vol. 170 Issue 7 Pg. 730-2 (Apr 01 1977) ISSN: 0003-1488 [Print] United States
• PMID: 870467 (Publication Type: Journal Article)

Chemical References

• Benzimidazoles
• Cambendazole
• Testosterone

Topics

• Animals
• Benzimidazoles (pharmacology)
• Cambendazole (pharmacology)
• Horses (physiology)
• Male
• Organ Size (drug effects)
• Reproduction (drug effects)
• Semen (drug effects)
• Spermatozoa (drug effects)
• Testis (anatomy & histology, drug effects)
• Testosterone (blood)
• Time Factors