Abstract |
A comparative study of individual resistance of rats to acute hypoxic hypoxia was performed. It was shown that individual resistance of the organism to hypoxia significantly decreases in the course of pregnancy. Limontar is shown to be active antihypoxant. Limontar administered during the last third of pregnancy stimulates protective-adaptive reactions in the females, thus increasing their resistance to hypoxia.
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Authors | A A Korneev, I A Komissarova, E M Chirkova, M A Koppel', O A Popova, G A Sheveleva, V G Filimonov |
Journal | Eksperimental'naia i klinicheskaia farmakologiia
(Eksp Klin Farmakol)
1995 Sep-Oct
Vol. 58
Issue 5
Pg. 34-6
ISSN: 0869-2092 [Print] Russia (Federation) |
Vernacular Title | Protektornoe deĭstvie limontara na beremennykh zhivotnykh pri ostroĭ gipoksicheskoĭ gipoksii. |
PMID | 8704587
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Citrates
- Drug Combinations
- Succinates
- limontar
- Citric Acid
- Succinic Acid
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Topics |
- Acute Disease
- Animals
- Atmosphere Exposure Chambers
- Citrates
(therapeutic use)
- Citric Acid
- Dose-Response Relationship, Drug
- Drug Combinations
- Drug Evaluation, Preclinical
- Female
- Hypoxia
(drug therapy, immunology)
- Immunity, Innate
(drug effects)
- Pregnancy
- Pregnancy Complications
(drug therapy, immunology)
- Rats
- Succinates
(therapeutic use)
- Succinic Acid
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