Abstract |
Bioassay-guided fractionation of the MeOH extract of Ornithogalum saundersiae bulbs led to the isolation of a new cholestane bisdesmoside with potent cytotoxic activities toward leukemia HL-60 and MOLT-4 cells. The structure was deduced mainly from spectroscopic information.
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Authors | Y Mimaki, M Kuroda, A Kameyama, Y Sashida, T Hirano, K Oka, K Koike, T Nikaido |
Journal | Bioscience, biotechnology, and biochemistry
(Biosci Biotechnol Biochem)
Vol. 60
Issue 6
Pg. 1049-50
(Jun 1996)
ISSN: 0916-8451 [Print] England |
PMID | 8695908
(Publication Type: Journal Article)
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Chemical References |
- Antineoplastic Agents, Phytogenic
- Cholestanes
- Gallic Acid
- 3,4,5-trimethoxybenzoic acid
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Topics |
- Antineoplastic Agents, Phytogenic
(chemistry, isolation & purification, pharmacology)
- Carbohydrate Conformation
- Carbohydrate Sequence
- Cholestanes
(chemistry, isolation & purification, pharmacology)
- Drug Screening Assays, Antitumor
- Gallic Acid
(analogs & derivatives, chemistry)
- HL-60 Cells
- Humans
- Magnetic Resonance Spectroscopy
- Molecular Sequence Data
- Plants
(chemistry)
- Tumor Cells, Cultured
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