Post-operative adhesions after laparoscopic electrosurgical treatment for polycystic ovarian syndrome with the application of Interceed to one ovary: a prospective randomized controlled study.

Abstract

In this prospective, randomized, controlled clinical study, 21 women underwent a second-look laparoscopy 2-11 weeks after standardized laparoscopic electrosurgical treatment for polycystic ovarian syndrome (PCOS). Following bilateral ovarian treatment, one ovary was randomly chosen to have Interceed applied to its surface using a specially designed applicator, with the other ovary serving as a control. Peri-adnexal adhesions of significant extent and severity developed in 57% of the women and 38% of the adnexa. The incidence of adhesions on the Interceed-treated side was 43%, while on the control side it was 33%. In addition, the extent and severity of the adhesions appeared to be similar on the Interceed-treated and control side. However, larger numbers would be required to determine statistically the effects of Interceed on de-novo adhesion formation after laparoscopic electrosurgical treatment of PCOS, as described here.

• Authors: H Saravelos, T C Li
• Journal: Human reproduction (Oxford, England) (Hum Reprod) Vol. 11 Issue 5 Pg. 992-7 (May 1996) ISSN: 0268-1161 [Print] England
• PMID: 8671376 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Cellulose, Oxidized
• INTERCEED

Topics

• Adult
• Cellulose, Oxidized (therapeutic use)
• Electrosurgery (adverse effects)
• Female
• Humans
• Laparoscopy (adverse effects)
• Ovarian Diseases (etiology)
• Polycystic Ovary Syndrome (surgery)
• Prospective Studies
• Tissue Adhesions (etiology, prevention & control)