Acute posterior multifocal placoid pigment epitheliopathy after acute group A streptococcal infection.

Abstract

PURPOSE:

We studied a case of acute posterior multifocal placoid pigment epitheliopathy in a 40-year-old man who had had an acute febrile illness.

METHODS:

The medical record was reviewed for clinical manifestations, course of disease, and laboratory findings, including results of fluorescein and indocyanine green angiography.

RESULTS:

The patient had the typical clinical course of acute posterior multifocal placoid pigment epitheliopathy with spontaneous resolution of posterior pole lesions and improvement in visual acuity from 20/60 to 20/20. The laboratory evaluation was remarkable for a rise in the anti-DNAse B antibody titer between initial and convalescent-phase serum samples, providing evidence of recent group A streptococcal infection.

CONCLUSION:

Although acute posterior multifocal placoid pigment epitheliopathy is often attributed to a postviral condition, this syndrome may also develop after an acute group A streptococcal infection.

• Authors: C Y Lowder, R E Foster, S M Gordon, F A Gutman
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 122 Issue 1 Pg. 115-7 (Jul 1996) ISSN: 0002-9394 [Print] United States
• PMID: 8659584 (Publication Type: Case Reports, Journal Article)

Chemical References

• Autoantibodies
• Deoxyribonucleases
• deoxyribonuclease B
• Indocyanine Green

Topics

• Acute Disease
• Adult
• Autoantibodies (analysis)
• Deoxyribonucleases (immunology)
• Fluorescein Angiography
• Fundus Oculi
• Humans
• Indocyanine Green
• Male
• Pigment Epithelium of Eye (immunology, pathology)
• Retinal Diseases (etiology, immunology, pathology)
• Streptococcal Infections (complications, immunology)
• Streptococcus pyogenes (enzymology)