[The interferon system in acute tick-borne encephalitis and effect on the dynamics of clinical laboratory indicators using different methods of interferon therapy].

Abstract

Study of the interferon system parameters, natural killer activity, and immunologic characteristics in patients with acute tick-borne encephalitis confirmed that addition of interferon preparations to combined therapy is pathogenetically justified. Reaferon was conducive to shortening of the manifest period of the disease and to alleviation of its symptoms, but it depressed its own interferonogenesis. Viferon had not only a positive impact on the time course of clinical parameters, but promoted a more active recovery of interferon production and immunologic parameters.

• Authors: V V Malinovskaia, G M Volegova, O Iu Ustinova
• Journal: Voprosy virusologii (Vopr Virusol) 1995 Sep-Oct Vol. 40 Issue 5 Pg. 234-8 ISSN: 0507-4088 [Print] Russia (Federation)
• Vernacular Title: Sistema interferona pri ostrom kleshchevom éntsefalite i vliianie na dinamiku kliniko-laboratornykh pokazateleĭ razlichnykh metodov interferonoterapii.
• PMID: 8659182 (Publication Type: English Abstract, Journal Article)

Chemical References

• Interferon Type I
• Recombinant Proteins
• Interferons

Topics

• Acute Disease
• Encephalitis, Tick-Borne (blood, therapy)
• Humans
• Interferon Type I (therapeutic use)
• Interferons (blood, immunology)
• Recombinant Proteins