Abstract | OBJECTIVE: To study the initial respiratory effects and those observed 18 months later after the inhalation of toxic and irritant substances in textile aerography workers. SUBJECTS: Seventeen patients (14 women and 3 men), with a mean age of 21 years (range: 18-38). METHODS: Initially, pulmonary effects were assessed by pathological (transbronchial biopsy and/or video-thoracoscopy) and functional findings [spirometry with lung volumes and study of diffusion capacity of CO (DLCO)]. Eighteen months later a challenge bronchial test with histamine was performed. RESULTS: Forty-one per cent of patients had pathologic lesions with intraalveolar fibrin, 35% had minimal non-specific lesions, 18% bronchiolitis obliterans with organized pneumonia (BOOP) and 6% pulmonary fibrosis and BOOP. Functional respiratory test showed two patients with a slight restrictive pattern, one patient with very severe restriction and six patients with low DLCO. The challenge tests was positive for 59% of patients. CONCLUSION: After the massive inhalation of irritant and/or toxic substances, patients presented different types of pathological response at pulmonary level. In our workers histological repairing lesions--of high or low degree--were found, BOOP being the lesions observed most frequently, and different patterns of functional involvement. Fifty-nine per cent of cases developed non-specific bronchial hyperreactivity consistent with a reactive airways dysfunction syndrome.
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Authors | A Solé Jover, M E b1rtínez Francés, P J Cordero Rodríguez, J Vallterra Musoles, V Macián Gisbert |
Journal | Revista clinica espanola
(Rev Clin Esp)
Vol. 196
Issue 3
Pg. 157-61
(Mar 1996)
ISSN: 0014-2565 [Print] Spain |
Vernacular Title | Efectos adversos sobre el tracto respiratorio en trabajadores de aerografía textil. |
PMID | 8650384
(Publication Type: Comparative Study, English Abstract, Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Biopsy
- Bronchial Hyperreactivity
(diagnosis)
- Cryptogenic Organizing Pneumonia
(chemically induced, diagnosis, pathology)
- Female
- Humans
- Lung
(pathology)
- Lung Diseases
(chemically induced, diagnosis, pathology)
- Male
- Occupational Diseases
(chemically induced, diagnosis, pathology)
- Paint
(adverse effects)
- Pulmonary Fibrosis
(chemically induced, diagnosis, pathology)
- Respiratory Function Tests
- Solvents
(adverse effects)
- Syndrome
- Textile Industry
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