Abstract | BACKGROUND: OBJECTIVE: The aim of the present study was to determine whether cimetidine is effective in the treatment of warts. METHODS: Seventy patients with multiple warts were included in a placebo-controlled, double-blind study. Patients were randomly allocated to treatment groups equally. The groups received cimetidine, 25 to 40 mg/kg daily, or placebo for 3 months. Patients were examined at monthly intervals. RESULTS: At the end of the therapy, 28 cimetidine-treated and 26 placebo-treated patients were examined to determine the efficacy of treatment. Cure rates obtained were 32% (9 of 28) in the cimetidine-treated group and 30.7% (8 of 26) in the placebo-treated group. No significant difference was found between cimetidine and placebo in effectiveness (p = 0.85). CONCLUSION: Our results show that cimetidine is no more effective than placebo in the treatment of patients with common warts.
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Authors | E Yilmaz, E Alpsoy, E Basaran |
Journal | Journal of the American Academy of Dermatology
(J Am Acad Dermatol)
Vol. 34
Issue 6
Pg. 1005-7
(Jun 1996)
ISSN: 0190-9622 [Print] United States |
PMID | 8647965
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Dermatologic Agents
- Histamine H2 Antagonists
- Placebos
- Cimetidine
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Topics |
- Adolescent
- Adult
- Child
- Child, Preschool
- Cimetidine
(administration & dosage, therapeutic use)
- Dermatologic Agents
(administration & dosage, therapeutic use)
- Double-Blind Method
- Female
- Histamine H2 Antagonists
(administration & dosage, therapeutic use)
- Humans
- Male
- Placebos
- Remission Induction
- Treatment Outcome
- Warts
(drug therapy)
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