High-dose oral dexamethasone therapy for chronic childhood idiopathic thrombocytopenic purpura.

Abstract

Because high-dose oral dexamethasone therapy has been reported to be effective for adults with idiopathic thrombocytopenic purpura, we assessed the short-term efficacy and toxicity of dexamethasone in seven children with chronic or refractory idiopathic thrombocytopenic purpura. Dexamethasone therapy was effective and well tolerated; further long-term studies are warranted.

• Authors: D M Adams, T R Kinney, E O'Branski-Rupp, R E Ware
• Journal: The Journal of pediatrics (J Pediatr) Vol. 128 Issue 2 Pg. 281-3 (Feb 1996) ISSN: 0022-3476 [Print] United States
• PMID: 8636831 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Anti-Inflammatory Agents
• Dexamethasone

Topics

• Adolescent
• Anti-Inflammatory Agents (administration & dosage, therapeutic use)
• Child
• Child, Preschool
• Dexamethasone (administration & dosage, adverse effects, therapeutic use)
• Dose-Response Relationship, Drug
• Female
• Humans
• Male
• Platelet Count
• Purpura, Thrombocytopenic (drug therapy)