Abstract | OBJECTIVE: PATIENT: RESULTS: Axillary lymph nodes showed both silicone lymphadenopathy, as well as classic morphologic and immunophenotypic features of KD. Screening tests for systemic autoimmune disorders were within normal range, suggesting that the unusual Kikuchi's-like immune reaction in one axillary lymph node was localized. The patient has no evidence of progressive immunologic disorders 3 years later. Subsequent lymph node biopsies showed silicone adenopathy with no evidence of KD. CONCLUSIONS: Our findings indicate that silicone compounds may be associated with transient abnormal immune reactions and lend further support to the hypothesis that KD represents an exuberant T-cell-mediated immune response to a variety of nonspecific stimuli.
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Authors | C E Sever, C P Leith, J Appenzeller, K Foucar |
Journal | Archives of pathology & laboratory medicine
(Arch Pathol Lab Med)
Vol. 120
Issue 4
Pg. 380-5
(Apr 1996)
ISSN: 0003-9985 [Print] United States |
PMID | 8619751
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Adult
- Autoimmune Diseases
(etiology)
- Axilla
- Breast Implants
(adverse effects)
- Female
- Histiocytes
(pathology)
- Humans
- Lymph Nodes
(pathology)
- Lymphadenitis
(etiology, pathology)
- Necrosis
(pathology)
- Prosthesis Failure
- Silicones
(adverse effects, analysis)
- Vacuoles
(chemistry, pathology)
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