Signet-ring cells associated with pseudomembranous colitis.

Abstract

After being treated for pneumonia with antibiotics, an 82-year-old man with a history of colonic carcinoma developed pseudomembranous colitis with toxic megacolon. In addition to the classic features of pseudomembranous colitis, the colon displayed signet-ring cells confined to the surface epithelium and crypts. A misdiagnosis of recurrent carcinoma was avoided after a review of the history and the endoscopic findings and by noting the location of the signet-ring cells.

• Authors: R Schiffman
• Journal: The American journal of surgical pathology (Am J Surg Pathol) Vol. 20 Issue 5 Pg. 599-602 (May 1996) ISSN: 0147-5185 [Print] United States
• PMID: 8619424 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Aged, 80 and over
• Biopsy
• Carcinoma, Signet Ring Cell (pathology)
• Colon (pathology)
• Colonic Neoplasms (pathology)
• Diagnosis, Differential
• Enterocolitis, Pseudomembranous (diagnosis, pathology)
• Humans
• Male
• Megacolon, Toxic (pathology)
• Neoplasm Recurrence, Local (pathology)