Abstract | BACKGROUND: OBJECTIVE: METHODS: RESULTS: Thirty-one (94%) of 34 control patients and 62 (89%) of 70 patients overall had blood cultures positive for organisms at either the 1-minute and or 3-minute mark following the initiation of surgery. The majority of cultures yielded gram-positive cocci. Cultures yielded polymicrobial organisms in 17 patients (24%). Although there was a wide range of severity of odontogenic disease, this did not correlate with results of blood cultures. However, there was a statistically significant difference in the incidence of blood cultures positive for organisms at both shorter (<3 minutes, P=.04) and longer (>6 minutes, P=.04) surgery times. There was not statistically significant difference in either the incidence of blood cultures positive for organisms or in the nature of organisms identified between the chlorhexidine and placebo groups. CONCLUSIONS: Single- tooth extraction should be expected to cause a bacteremia regardless of the status of the dentition or periodontium. Mouth rinses with chlorhexidine not significantly alter the number of positive blood cultures or the nature of the organisms at either of the two blood drawings.
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Authors | P B Lockhart |
Journal | Archives of internal medicine
(Arch Intern Med)
Vol. 156
Issue 5
Pg. 513-20
(Mar 11 1996)
ISSN: 0003-9926 [Print] United States |
PMID | 8604957
(Publication Type: Clinical Trial, Clinical Trial, Phase II, Journal Article, Randomized Controlled Trial, Review)
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Chemical References |
- Anti-Infective Agents, Local
- Placebos
- Chlorhexidine
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Topics |
- Adult
- Aged
- Anti-Infective Agents, Local
(administration & dosage, pharmacology)
- Bacteremia
(epidemiology, microbiology, prevention & control)
- Bacteria, Aerobic
(isolation & purification)
- Bacteria, Anaerobic
(isolation & purification)
- Chlorhexidine
(administration & dosage, pharmacology)
- Double-Blind Method
- Female
- Humans
- Incidence
- Male
- Middle Aged
- Mouth
(microbiology)
- Placebos
- Tooth Extraction
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