Inhibitory effect of iridoids on Epstein-Barr virus activation by a short-term in vitro assay for anti-tumor promoters.

Abstract

The in vitro anti-tumor promoting effect of the methanolic extracts of iridoids containing three plants and several pure iridoids isolated from other plants, has been evaluated. The alcoholic extracts of Paederia scandens, P. scandens var. mairei and the Ayurvedic herbal remedy Picrorhiza kurrooa were tested against the Epstein-Barr virus. Among the 15 iridoids evaluated, the glycoside, paederoside, displayed the highest order of anti-tumor promoting activity.

• Authors: G J Kapadia, S C Sharma, H Tokuda, H Nishino, S Ueda
• Journal: Cancer letters (Cancer Lett) Vol. 102 Issue 1-2 Pg. 223-6 (Apr 19 1996) ISSN: 0304-3835 [Print] Ireland
• PMID: 8603374 (Publication Type: Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Chemical References

• Anticarcinogenic Agents
• Antiviral Agents
• Glucosides
• Iridoids
• Plant Extracts
• Pyrans

Topics

• Anticarcinogenic Agents (therapeutic use)
• Antiviral Agents (therapeutic use)
• Glucosides (therapeutic use)
• Herpesvirus 4, Human (drug effects, growth & development)
• Iridoids
• Plant Extracts (therapeutic use)
• Pyrans (therapeutic use)
• Time Factors
• Virus Activation (drug effects)