Abstract | OBJECTIVE: PATIENTS AND METHODS: RESULTS: Using efficacy analysis, 41 of 42 duodenal ulcers (98%; 95% CI 0.87-1.00) were healed after one week of treatment. H. pylori was eradicated in 40 of 42 patients (95%; 95% CI 0.84-1.00). Two patients with healed ulcers showed a persistent infection, whereas H. pylori was eradicated in the one patient with persisting ulcer. Using intention-to-treat analysis, ulcer healing was achieved in 41 of 45 (91%; 95% CI 0.79-0.98) and H. pylori eradication in 40 of 45 patients (89%; 95% CI 0.76-0.96). After a mean of five days, 40 of 41 patients (98%; 95% CI 0.87-1.00) with ulcer healing became completely pain-free. CONCLUSIONS:
|
Authors | K Schütze, E Hentschel |
Journal | Zeitschrift fur Gastroenterologie
(Z Gastroenterol)
Vol. 33
Issue 11
Pg. 651-3
(Nov 1995)
ISSN: 0044-2771 [Print] Germany |
PMID | 8600661
(Publication Type: Journal Article)
|
Chemical References |
- 2-Pyridinylmethylsulfinylbenzimidazoles
- Anti-Bacterial Agents
- Anti-Ulcer Agents
- Penicillins
- Lansoprazole
- Amoxicillin
- Clarithromycin
- Omeprazole
|
Topics |
- 2-Pyridinylmethylsulfinylbenzimidazoles
- Adolescent
- Adult
- Aged
- Amoxicillin
(administration & dosage, adverse effects)
- Anti-Bacterial Agents
(administration & dosage, adverse effects)
- Anti-Ulcer Agents
(administration & dosage, adverse effects)
- Clarithromycin
(administration & dosage, adverse effects)
- Dose-Response Relationship, Drug
- Drug Administration Schedule
- Drug Therapy, Combination
- Duodenal Ulcer
(drug therapy)
- Duodenoscopy
- Female
- Helicobacter Infections
(drug therapy)
- Helicobacter pylori
(drug effects)
- Humans
- Lansoprazole
- Male
- Middle Aged
- Omeprazole
(administration & dosage, adverse effects, analogs & derivatives)
- Penicillins
(administration & dosage, adverse effects)
- Pilot Projects
- Treatment Outcome
|