| Abstract | Immunological reconstruction was studied in children aged 6 years after the second revaccination with absorbed, pertussis-diphtheria-tetanus vaccine (APDT) in a strictly controlled trial. Antipertussis protective antibodies were determined in the sera in the passive hemagglutination test and the antigen neutralization test, whose results were characterized by the following regularities: the average (1:160--1:640) and the high (1:1280 and over) antibody titres were recorded 1 to 1.5 months after the vaccination in 46.9--48.9% of the persons vaccinated. Determination of the changes of the immunoglobulins A, M, and G at various periods after the second revaccination demonstrated that 1 to 1.5 months after the revaccination (that is at the peak of the antipertussis antibodies formation) 55.7--50.0% of the children displayed an elevation of the IgA and IgM against the background of the IgG reduction in 69.7% of cases. |
| Authors | E A Baeva, I Z Aleksandrova, T S Selezneva |
| Journal | Zhurnal mikrobiologii, epidemiologii, i immunobiologii
(Zh Mikrobiol Epidemiol Immunobiol)
Issue 2
Pg. 104-8
(Feb 1977)
ISSN: 0372-9311 USSR |
| Vernacular Title | Osobennosti immunologicheskoĭ perestroĭki protiv kokliusha u deteĭ posle vtoroĭ revaktsinatsii AKDS-vaktsinoĭ |
| PMID | 857515
(Publication Type: English Abstract, Journal Article)
|
| Chemical References |
- Antibodies, Bacterial
- Immunoglobulin A
- Immunoglobulin G
- Immunoglobulin M
- Pertussis Vaccine
|
| Topics |
- Antibodies, Bacterial
(analysis)
- Child
- Hemagglutination Tests
- Humans
- Immunization Schedule
- Immunization, Secondary
- Immunoglobulin A
(analysis)
- Immunoglobulin G
(analysis)
- Immunoglobulin M
(analysis)
- Neutralization Tests
- Pertussis Vaccine
(administration & dosage)
- Time Factors
- Whooping Cough
(immunology, prevention & control)
|
