[Flubiprofen vs dipyrone combined with hyoscine: the analgesic efficacy in renal colic].

Abstract

OBJECTIVE:

We compared the efficacy of flurbiprofen (NSAID) versus dipirone + hyoscine N-butylbromide in the treatment of nephric colic.

METHODS:

The study comprised 135 patients, aged 18 to 75 yrs, with intense nephric colic. The patients were observed 60 min after a single IM dose of 150 mg flurbiprofen (n = 67) or 2 gm dipirone + 20 mg hyoscine N-butylbromide.

RESULTS:

Both treatment modalities were well-tolerated and afforded significant pain relief. Flurbiprofen, however, was faster-acting and superior to dipirone + hyoscine in the overall evaluation of good and excellent therapeutic response rates.

CONCLUSION:

The results of the study show that IM flurbiprofen is a useful alternative to dipirone + hyoscine N-butylbromide in the treatment of nephric colic.

• Authors: M J Mora Durban, J Extramiana Cameno, M Arrizabalaga Moreno, P Paniagua Andrés, J Camp Herrero, J Milla Santos, F del Nogal Saez, F Gimeno Albo, E Moreno Carretero, R Domínguez Granados
• Journal: Archivos espanoles de urologia (Arch Esp Urol) Vol. 48 Issue 9 Pg. 867-73 (Nov 1995) ISSN: 0004-0614 [Print] Spain
• Vernacular Title: Flubiprofeno vs dipirona asociada a hioscina: eficacia analgésica en el cólico nefrítico.
• PMID: 8554391 (Publication Type: Clinical Trial, Clinical Trial, Phase III, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Butylscopolammonium Bromide
• Flurbiprofen
• Dipyrone
• Scopolamine

Topics

• Adolescent
• Adult
• Aged
• Analysis of Variance
• Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)
• Butylscopolammonium Bromide (therapeutic use)
• Chi-Square Distribution
• Colic (drug therapy)
• Dipyrone (therapeutic use)
• Double-Blind Method
• Drug Therapy, Combination
• Female
• Flurbiprofen (therapeutic use)
• Humans
• Kidney Diseases (drug therapy)
• Male
• Middle Aged
• Scopolamine (therapeutic use)