Abstract |
Most of the Coxiella burnetii isolates (72 of 80) available in our institute share a 2.1 kb NotI fragment. Sequence analysis revealed two incomplete open reading frames (ORF) for putative genes hemA and bcR coding for glutamyl-tRNA-reductase and bicyclomycin resistance protein, respectively. Upon completing the ORF for the hemA gene by sequencing the adjacent NotI/EcoRI fragment a third ORF for the putative prfA gene was determined coding for release factor 1, an enzyme catalysing the last step in protein biosynthesis.
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Authors | H Willems, D Thiele, H Krauss |
Journal | European journal of epidemiology
(Eur J Epidemiol)
Vol. 11
Issue 5
Pg. 559-61
(Oct 1995)
ISSN: 0393-2990 [Print] Netherlands |
PMID | 8549730
(Publication Type: Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- Bridged Bicyclo Compounds, Heterocyclic
- Escherichia coli Proteins
- Oncogene Proteins
- Peptide Termination Factors
- Proto-Oncogene Proteins
- prfA protein, E coli
- Aldehyde Oxidoreductases
- glutamyl tRNA reductase
- DNA modification methylase EcoRI
- Site-Specific DNA-Methyltransferase (Adenine-Specific)
- Protein-Tyrosine Kinases
- Proto-Oncogene Proteins c-bcr
- Deoxyribonucleases, Type II Site-Specific
- GCGGCCGC-specific type II deoxyribonucleases
- bicozamycin
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Topics |
- Aldehyde Oxidoreductases
(genetics)
- Animals
- Anti-Bacterial Agents
(pharmacology)
- Bridged Bicyclo Compounds, Heterocyclic
(pharmacology)
- Cells, Cultured
- Chlorocebus aethiops
- Coxiella burnetii
(genetics)
- Deoxyribonucleases, Type II Site-Specific
(genetics)
- Drug Resistance, Microbial
(genetics)
- Escherichia coli
(genetics)
- Escherichia coli Proteins
- Genes, Bacterial
(genetics)
- Genetic Linkage
- Molecular Sequence Data
- Oncogene Proteins
(genetics)
- Open Reading Frames
(genetics)
- Peptide Termination Factors
(genetics)
- Protein-Tyrosine Kinases
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-bcr
- Salmonella typhimurium
(genetics)
- Sequence Analysis, DNA
- Sequence Homology, Nucleic Acid
- Site-Specific DNA-Methyltransferase (Adenine-Specific)
(genetics)
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