[A complex antibiotic preparation obtained from a medicinal plant from the family Asteraceae].

Abstract

Data of in vitro and in vivo investigations of antimicrobial activity of preparation K carried out both by the authors and by other researchers and pharmacological properties of this preparation have been summarized. Preparation K has been obtained from medicinal plant of the Asteraceae family. It is a natural composition of two antibiotics and of a number of minor compounds. The preparation possesses a wide spectrum of biological action. It is antimicrobially active against gram-positive bacteria, some species of gram-negative bacteria, fungi-dermatophytes including antibiotic-resistant strains. It is not toxic for animals, stimulates some defensive reactions of macroorganism, has immunomodulating, anti-inflammatory, anti-exudative, keratolytic properties. Preparation K is efficient for treatment of experimental mycoses of animals and is clinically tested as a local agent for treatment of dermatomycoses.

• Authors: V V Smirnov, A S Bondarenko, G T Petrenko, V A Prikhod'ko, O V Evseenko, L V Pavlenko
• Journal: Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) (Mikrobiol Z) 1995 Jul-Aug Vol. 57 Issue 4 Pg. 73-82 ISSN: 1028-0987 [Print] Ukraine
• Vernacular Title: Kompleksnyĭ antibioticheskiĭ preparat, poluchennyĭ iz lekarstvennogo rasteniia semeĭstva Asteraceae.
• PMID: 8548074 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Antibiotics, Antitubercular
• Antifungal Agents
• Plant Extracts
• Preparation K

Topics

• Animals
• Antibiotics, Antitubercular (pharmacology, therapeutic use, toxicity)
• Antifungal Agents (pharmacology, therapeutic use, toxicity)
• Bacteria (drug effects)
• Drug Evaluation, Preclinical
• Fungi (drug effects)
• Humans
• Plant Extracts (pharmacology, therapeutic use, toxicity)
• Plants, Medicinal