[A deficient T-cell count and its elimination during the treatment and prevention of infections].

Abstract

The results of the study of the parameters of the immune system in persons suffering from frequent infections, bacteriocarriers and persons with nonspecific infections are presented. The study revealed that T-cell deficiency of the 2nd and 3rd degrees could be regarded as the universal marker of decreased immune reactiveness. Sodium nucleinate was found to be capable of stimulating the T-cell element of immunity and antibody formation, which made it possible to achieve a considerable decrease in morbidity rate. Sodium nucleinate was shown to be highly effective in the prophylaxis of acute respiratory viral infections, carrier state and in the sanitation of purulent foci of infection.

• Authors: A M Zemskov, V M Zemskov, V A Platonova, E D Chertok, A M Tupkalova, A T Vysotskaia, T A Zemskova, A A Degtiarev, S E Furgal, Iu A Evstratov
• Journal: Zhurnal mikrobiologii, epidemiologii i immunobiologii (Zh Mikrobiol Epidemiol Immunobiol) 1995 Sep-Oct Issue 5 Pg. 68-71 ISSN: 0372-9311 [Print] Russia (Federation)
• Vernacular Title: Defitsit kolichestva T-kletok i ego ustranenie v protsesse lecheniia i profilaktiki infektsiĭ.
• PMID: 8525738 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Biomarkers
• Nucleic Acids
• sodium nucleinate

Topics

• Acute Disease
• Adjuvants, Immunologic (administration & dosage)
• Adolescent
• Adult
• Bacterial Infections (drug therapy, immunology, prevention & control)
• Biomarkers
• Carrier State (drug therapy, immunology, prevention & control)
• Child
• Child, Preschool
• Chronic Disease
• Female
• Humans
• Infant
• Lymphocyte Count
• Male
• Middle Aged
• Military Personnel
• Nucleic Acids (administration & dosage)
• Russia
• T-Lymphocytes (immunology)